Regulatory ·

An FDA panel voted yes on BPC-157. It's still not legal to compound.

In July, FDA's compounding advisory committee narrowly backed BPC-157, TB-500 and MOTS-c. The vote is only advice, FDA's own reviewers had doubts, and sport rules haven't changed.

What happened

On July 23, 2026, FDA’s Pharmacy Compounding Advisory Committee voted on whether pharmacies should be allowed to make (compound) several peptides. The panel narrowly voted for BPC-157 and TB-500 (8 to 6, with one abstention) and MOTS-c (7 to 5, with two abstentions).

  • The vote is advice, not a decision. The committee advises FDA. A peptide only becomes eligible for compounding once FDA formally adds it to its list, and FDA hasn’t finalized that decision.
  • FDA’s own reviewers had doubts. Before the meeting, FDA’s scientists raised quality and safety concerns about BPC-157, and recommended against adding TB-500 and MOTS-c because there’s so little human data.
  • It’s not an approved medicine either way. Compounding eligibility wouldn’t make BPC-157 an FDA-approved drug or prove that it works.

If you compete

None of this changes anti-doping rules. BPC-157 and TB-500 remain banned at all times by the World Anti-Doping Agency, and MOTS-c is banned as a metabolic modulator.

Learn more

Read what the research actually shows in our BPC-157, TB-500 and MOTS-c guides, or compare them on the Peptide Evidence Scorecard.

Sources

  1. FDA Panel Backs 6 Peptides for Compounding (July 31, 2026) · The American Journal of Managed Care (AJMC)
  2. FDA Briefing Document: Evaluation of BPC-157 for the 503A Bulk Drug Substances List (May 11, 2026) · U.S. Food and Drug Administration
  3. FDA Briefing Document: Evaluation of TB-500 for the 503A Bulk Drug Substances List · U.S. Food and Drug Administration
  4. FDA Briefing Document: Evaluation of MOTS-c for the 503A Bulk Drug Substances List (May 11, 2026) · U.S. Food and Drug Administration
  5. World Anti-Doping Code International Standard: Prohibited List 2026 · World Anti-Doping Agency (copy hosted by the International Testing Agency)
Tissue repair

BPC-157

A peptide based on a protein in human stomach juice, with encouraging animal results for healing tendons, muscle, and the gut.

Preclinical34 refs · 6 min
Tissue repair

TB-500

A lab-made piece of thymosin beta-4, a natural repair protein that has shown promise in animal studies and early human trials.

Preclinical28 refs · 7 min
Mitochondrial peptide

MOTS-c

A peptide encoded in mitochondrial DNA that acts like a metabolic hormone, boosted by exercise and studied in mice for metabolism and aging.

Preclinical21 refs · 5 min